Okay Twitter, you asked for it! Here is the updated vaccine comparison & "side effects"

I chose the highest prevalence cohort, which was the younger group.

Moderna comes with more side effects than Pfizer, especially after dose 2 though overall still not more than Shingrix.
COVID-19 VACCINES: PFIZER VS MODERNA
Some background basics:

*NEITHER CAN GIVE YOU COVID-19, AND NEITHER ALTER YOUR GENES.

Moderna is definitely easier on the supply chain.
1 case of severe COVID-19 in Pfizer vaccine arm (though did not require hospitalization) vs 0 in Moderna.
Moderna has less side effects after Dose 1
But... Moderna has more side effects after Dose 2. Again, side effects are to be expected with reactogenicity.
Grade 3 side effects also more prevalent in Moderna trial at 4.1% overall vs 1.5%. Grade 3 typically means enough to impair productivity.
Overall, the vaccines are roughly equivalent with some clinical trial caveats.

These still require real-world application and data!

Data from FDA package inserts and EUA applications.

-Cheers to my friend Bryan Brown for the comic style graphic.
You can follow @JesseOSheaMD.
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