Meta-analysis of 54 studies with 77 ,758 participants, the estimated mean secondary attack rate (SAR) for household contacts was 16.4% (95% CI, 13.4%-19.6%) & family contacts was 17.4% (95% CI, 12.7%-22.5%)
Household and family SARs were >3 times higher than for close contacts (4.8%; 95% CI, 3.4%-6.5%; P < .001)
Estimated mean household SAR from symptomatic index cases (18.0%; 95% CI, 14.2%-22.1%) was significantly higher than from asymptomatic or presymptomatic index cases (0.7%; 95% CI, 0%-4.9%; P < .001), although there were few studies in the latter group.
The estimated mean household SAR was significantly higher to adult contacts (28.3%; 95% CI, 20.2%-37.1%) than to child contacts (16.8%; 95% CI, 12.3%-21.7%; P < .001).
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