Hot take: Pharmacist love to tout this to patients, but their is minimal truth, this may be more medical myth than fact if you believe in evidence. (1/3) https://twitter.com/PharmaFactz/status/1334928510692028417
1. All reports seem to be anecdote, just as likely to be from ETOH/patient dz: https://bit.ly/2VDUF4R , https://bit.ly/3onXa7F
2. Controlled human data shows no reaction: https://bit.ly/33INqgg
3. Animal data is meh, ↑ in GI Acetaldehyde not systemic https://bit.ly/3gmwT6Y
2. Controlled human data shows no reaction: https://bit.ly/33INqgg
3. Animal data is meh, ↑ in GI Acetaldehyde not systemic https://bit.ly/3gmwT6Y
2/2
1. Good data supporting no rxn>data for rxn
2. IF rxn w/etoh occurs, not from "disulfiram" ↑ Acetaldehyde (2, 3)
3. IF exists, is VERY rare, calling in to ? counseling pt to avoid EVERY thing with EToH (yes you know an RPH who says avoid mouthwash dont lie)
1. Good data supporting no rxn>data for rxn
2. IF rxn w/etoh occurs, not from "disulfiram" ↑ Acetaldehyde (2, 3)
3. IF exists, is VERY rare, calling in to ? counseling pt to avoid EVERY thing with EToH (yes you know an RPH who says avoid mouthwash dont lie)