Yi-Chen Lai discusses antibody mediated autoimmune encephalitis in the #PedsICU
This is development of antibodies to neural tissues
Think about this in kids with:
- acute encephalopathy
- new neurological defects
- Status epilepticus
Many will not need PICU
#WFPICCS20
This is development of antibodies to neural tissues
Think about this in kids with:
- acute encephalopathy
- new neurological defects
- Status epilepticus
Many will not need PICU
#WFPICCS20
The data shows a significant proportion of encephalitis in childhood is due to autoimmune diseases, with many antibodies detected
The three main autoantibodies associated in children have some specific features... see table below!
#PedsICU #WFPICCS20
The three main autoantibodies associated in children have some specific features... see table below!
#PedsICU #WFPICCS20
The management of autoimmune encephalitis is a based around targeting the autoantibodies
What is key is earlier treatment is associated with better outcomes (this means need to think about and diagnose!)
#PedsICU #WFPICCS20
What is key is earlier treatment is associated with better outcomes (this means need to think about and diagnose!)
#PedsICU #WFPICCS20