Yi-Chen Lai discusses antibody mediated autoimmune encephalitis in the #PedsICU

This is development of antibodies to neural tissues

Think about this in kids with:
- acute encephalopathy
- new neurological defects
- Status epilepticus

Many will not need PICU

#WFPICCS20
The data shows a significant proportion of encephalitis in childhood is due to autoimmune diseases, with many antibodies detected

The three main autoantibodies associated in children have some specific features... see table below!

#PedsICU #WFPICCS20
Yi-Chen Lai discusses the proposed classification for autoimmune encephalitis

#PedsICU #WFPICCS20
The management of autoimmune encephalitis is a based around targeting the autoantibodies

What is key is earlier treatment is associated with better outcomes (this means need to think about and diagnose!)

#PedsICU #WFPICCS20
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