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I was about closing for the day when they drove in, in a way Odogwu usually call fast and furious style.His eyes was already yellow and his skin is already changing color!
From what i gathered he took paracetamol after drinking alot of alcohol at the party
His liver is failing
From what i gathered he took paracetamol after drinking alot of alcohol at the party
His liver is failing
However, there’s every tendency of developing headache after consuming a certain amount of alcohol, especially after binge drinking. When this happens, the next thing most people do is to take paracetamol, the most common analgesic for headache.
....it can be very lethal.
Now Let Me Explain...
When you take 2 tablets of paracetamol, they are absorbed into the bloodstream from the stomach and small intestines and taken to the liver. In the liver, certain enzymes convert most of the drug into a less harmful form which...
Now Let Me Explain...
When you take 2 tablets of paracetamol, they are absorbed into the bloodstream from the stomach and small intestines and taken to the liver. In the liver, certain enzymes convert most of the drug into a less harmful form which...
carries out the headache-relieving function before being excreted out of the body in urine.
This less harmful form of paracetamol produces other chemical substances while carrying out its pain-relieving function and in the process of being converted into a form that can be...
This less harmful form of paracetamol produces other chemical substances while carrying out its pain-relieving function and in the process of being converted into a form that can be...
passed out in urine. One of these chemical substances (byproducts) ends up being turned into a toxic compound that can damage the liver cells and tissues. To prevent this damage, the liver produces another substance, called glutathione, to sort of neutralize this toxic compound.
In the same vein,alcohol is a chemical substance that is also acted upon by the liver when consumed. A group of liver enzymes breaks down any alcohol in the body into a less harmful form. But just like paracetamol, alcohol breakdown produces some toxic substances.
@aproko_doctor
@aproko_doctor
And the liver uses the same substance, glutathione, to neutralise these toxic substances.
So What Happens When You Take Paracetamol after Drinking Alcohol?
So What Happens When You Take Paracetamol after Drinking Alcohol?
If you are just an occasional drinker, that is you take alcohol once in a while and starts having a headache, you can take the normal adult dose for paracetamol for a day or two. And you are fine without anything to worry about concerning your liver.
But if you are heavy or chronic alcohol drinker, then you may have to be careful with how much paracetamol to take whenever you start having a headache after drinking. Why?
Heavy alcohol drinking over a long period of time, on its own, damages the liver cells and tissues...
Heavy alcohol drinking over a long period of time, on its own, damages the liver cells and tissues...
...causing what is known as alcoholic liver disease.
In addition, chronic heavy alcohol drinking drastically reduces the liver stores of, and its capacity to produce, the substance called glutathione needed to neutralise the toxic byproducts of both alcohol and paracetamol.
In addition, chronic heavy alcohol drinking drastically reduces the liver stores of, and its capacity to produce, the substance called glutathione needed to neutralise the toxic byproducts of both alcohol and paracetamol.
A headache from heavy alcohol drinking especially in a chronic alcoholic is usually severe. Hence, there’s the tendency to take as many tablets of the commonly available paracetamol as possible and as long as possible to get relief. This is very dangerous because:
The liver which is probably under attack from heavy alcohol drinking has less amount of, and a reduced capacity to produce, glutathione. The result is the toxic byproduct of paracetamol breakdown causing further damage to a liver already under attack.
The toxic byproduct of alcohol further overwhelms the remaining glutathione trying to neutralise the toxic byproduct of the ingested paracetamol, making the liver more vulnerable to damage.
Therefore, if you’re a regular alcohol drinker or a heavy drinker or someone who engages in binge drinking, you should avoid taking paracetamol when you have a hangover. Panadol should be avoided too as it’s just paracetamol with a different name:
they both contain the same chemical compound known as acetaminophen.
There are other classes of pain relievers whose breakdown in the body does not affect the liver the way that of paracetamol does. They include ibuprofen and diclofenac.
There are other classes of pain relievers whose breakdown in the body does not affect the liver the way that of paracetamol does. They include ibuprofen and diclofenac.
However, if you have a peptic ulcer disease (you experience a burning sensation at the upper part of your tummy either before or after food), you should avoid ibuprofen, diclofenac and other pain-relievers under the same class known as NSAIDS.
They worsen ulcer and can also cause bleeding in the stomach as a side effect.
Naturally humans love to merry, we love to party and feel good. Most of this times we consume alot of alcohol.
Naturally humans love to merry, we love to party and feel good. Most of this times we consume alot of alcohol.
Christmas is now fast approaching and alot of alcohol will be available and there is every tendency that people will consume large quantities of alcohol and other alcoholic beverages
To be on the safe side, drink in moderation and responsibly this festive season.
To be on the safe side, drink in moderation and responsibly this festive season.
