![Polizeiautos mit drehendem Licht đ¨](https://abs.twimg.com/emoji/v2/72x72/1f6a8.png)
Very exciting!
The authors describe the discovery of a live virus-vectored
#SARSCoV2 vaxx candidate using the YF17D vaccine as vector to express a non-cleavable pre-fusion form of the SARS-CoV-2 Spike antigen.
Been waiting for this, let me tell you why
https://www.nature.com/articles/s41586-020-3035-9
![Fettes weiĂes Häkchen â](https://abs.twimg.com/emoji/v2/72x72/2705.png)
Yellow Fever 17D=small RNA live-attenuated virus
![Fettes weiĂes Häkchen â](https://abs.twimg.com/emoji/v2/72x72/2705.png)
YF17D vaccine induces broad polyfunctional humoral & cell-mediated immune responses that may result in life-long protection following a single vaccine dose in nearly all vaccinees! Yes that's right - Lifelong
![Fettes weiĂes Häkchen â](https://abs.twimg.com/emoji/v2/72x72/2705.png)
These favorable characteristics translate also to vectored-vaccines based on the YF17D backbone!!!
![Fettes weiĂes Häkchen â](https://abs.twimg.com/emoji/v2/72x72/2705.png)
YF17D is used as vector in two licensed human vaccines, generated by swapping genes encoding the YF17D surface antigens for JEV or dengue viruses.
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