Interested in drug combinations for cancer? My curated Gold Standard dataset in @canSAR_ICR (‘canSynergize’) is now available... (1/n) 🧵
... containing details of 300,000+ drug combinations in cancer cell lines manually extracted from 100+ publications, drug interactions are scored quantitatively and qualitatively... (2/n)
... Yes, I did read a lot of papers and extract data from tables and PDFs. Yes, it did take a long time 😄 drug target annotation is included, with full links to @canSAR_ICR drug and target pages...
... plus curated cell line names, curated cancer types and Pubmed IDs. That’s not all...
... it also contains details of 1400+ clinical trials registered on http://clinicaltrials.gov  where pairwise combinations of targeted drugs are/have been used to treat #cancers...
... data is available here (bottom of the page) and discussed in the latest @canSAR_ICR paper: https://cansarblack.icr.ac.uk/faq  ...
canSAR | the Cancer Drug Discovery Platform

Frequently Asked Questions | the Cancer Drug Discovery Platform | ICR CRUK Cancer Therapeutics Unit | canSAR

https://cansarblack.icr.ac.uk/faq
... canSAR: update to the cancer translational research and drug discovery knowledgebase https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa1059/5997433#.X8IpEP8alyU.twitter

Enjoy! #CancerResearch #MachineLearning #DataScience
You can follow @LizzieCoker.
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