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Pfizer’s vaccine has headlined being "more than 90% effective.”.
This is slightly misleading.
90% is the relative risk reduction. But the absolute risk reduction of the Pfizer’s vaccine is approx 0.4%.
The vaccine reduces your personal risk of infection by COVID by 0.4%.
This is slightly misleading.
90% is the relative risk reduction. But the absolute risk reduction of the Pfizer’s vaccine is approx 0.4%.
The vaccine reduces your personal risk of infection by COVID by 0.4%.
This translates to a Number Needed To Vaccinate = 256.
"To prevent 1 Covid case 256 individuals must get the vaccine; the other 255 individuals derive no benefit, but are subject to vaccine adverse effects."
"To prevent 1 Covid case 256 individuals must get the vaccine; the other 255 individuals derive no benefit, but are subject to vaccine adverse effects."
This summary of risk (not COVID related) by http://patient.info is great.
The NNTV above is calculated using the number of positive CASES.
We do not know whether these cases are symptomatic or not.
If endpoints such as quality of life, hospitalisation or death were used – then I predict an even higher NNTV.
We do not know whether these cases are symptomatic or not.
If endpoints such as quality of life, hospitalisation or death were used – then I predict an even higher NNTV.
Other NNTV, for interest sake:
-314,000 to 2.7 million for rabies acquired through bedroom bats.
-38,610 infants would need to be vaccinated in order to prevent one case of serogroup B invasive meningococcal disease.
-302 individuals to prevent ONE DEATH due to influenza.
-314,000 to 2.7 million for rabies acquired through bedroom bats.
-38,610 infants would need to be vaccinated in order to prevent one case of serogroup B invasive meningococcal disease.
-302 individuals to prevent ONE DEATH due to influenza.
In comparison, the COVID vaccine seems better.
However, there are other things to consider:
-Cost analysis (this should not be rushed)
-How will the vaccine be administered?
-Effectiveness in the population and sub-sets
-Long term side-effects
However, there are other things to consider:
-Cost analysis (this should not be rushed)
-How will the vaccine be administered?
-Effectiveness in the population and sub-sets
-Long term side-effects
