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The final version of our paper on GGT is finally out 
Check it our if you are interested in risk stratification in PBC (1) 
@MCarbone_80 @MarcoMarzioni74 @AutoImmuneLiver @dougton @tony_bruns @KowdleyMd @NikosGatselis https://www.cghjournal.org/article/S1542-3565(20)31083-1/fulltext#.X7FEms7tA0I.twitter
Check it our if you are interested in risk stratification in PBC (1) @MCarbone_80 @MarcoMarzioni74 @AutoImmuneLiver @dougton @tony_bruns @KowdleyMd @NikosGatselis https://www.cghjournal.org/article/S1542-3565(20)31083-1/fulltext#.X7FEms7tA0I.twitter
We should move toward normalisation of serum ALP levels; yet, while we continue to use dichotomous criteria such as ALP < 1.5/1.67 x ULN in clinic - maybe due to constrained second-line tx regulations or convenience... 
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...we should take special care of those patients with ALP levels < 1.5 x ULN and elevated GGT (3.2 x ULN). These have worse prognosis than those with ALP<1.5 & GGT < 3.2. What to do then? Exclude NAFLD/MAFLD/alcohol/drugs; then consider to escalate treatment for PBC...
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