Haembase updated with the new BSH Hairy Cell Leukaemia guideline, why not try the questions in the thread below before taking a look?
https://haembase.com/hairy-cell-leukaemia
https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.17055

#haematology #FRCPath #blooducation
Hairy Cell Leuk — HaemBase

https://haembase.com/hairy-cell-leukaemia
1. Hairy cell leukaemia makes up what proprotion of all leukaemias?
2. The 'Hairy Cell Panel' refers to which four immunophenotyping markers?
3. The presence of the BRAFV600E mutations is a disease-defining event
4. Moxetumumab pasudotox is expected to get a UK license later this year. What is the antibody target against?
Answers:
1. 2%.
2. CD11c, CD25, CD103, CD123. If 3 or 4 of the panel are positive it helps distinguish HCL from other LPDs.
3. True
4. CD22. The antibody is conjugated with a pseudomonas exotoxin.
Thanks for reading, corrections welcome https://haembase.com/hairy-cell-leukaemia
Hairy Cell Leuk — HaemBase

https://haembase.com/hairy-cell-leukaemia
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