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Fascinating study of a family of 5 who survived SARS-CoV-2 infection. Parents got infected first, gave it to children of 9, 7 & 5 years.
Only the mother made adequate neutralising antibodies. Children showed immune response, but were PCR negative.
1/3 https://www.nature.com/articles/s41467-020-19545-8
Only the mother made adequate neutralising antibodies. Children showed immune response, but were PCR negative.
1/3 https://www.nature.com/articles/s41467-020-19545-8
cont'd
The youngest girl of 5 years slept with the parents throughout. She showed robust antibody response, but did not develop any symptoms.
Her older brothers got symptoms in spite of physical distancing (to the extent possible)
2/3
The youngest girl of 5 years slept with the parents throughout. She showed robust antibody response, but did not develop any symptoms.
Her older brothers got symptoms in spite of physical distancing (to the extent possible)
2/3
cont’d
This study is special because it demonstrates the immunology profile of a common real life scenario: of a young family living together.
Conclusion:
1. Children can go though infection without testing PCR positive.
2. Asymptomatic infections occur in children.
3/3
This study is special because it demonstrates the immunology profile of a common real life scenario: of a young family living together.
Conclusion:
1. Children can go though infection without testing PCR positive.
2. Asymptomatic infections occur in children.
3/3
