Read on Twitter
inhaled nebulised interferon beta-1a (SNG001)
(aka. for the general term: β-interferon, Interferon-beta, Beta-Interferon, Interferon-β, IFN-β)
(It MIGHT possibly help against Covid-19, but remember: this is not medical advice!, check everything & talk to your doctor!)
(aka. for the general term: β-interferon, Interferon-beta, Beta-Interferon, Interferon-β, IFN-β)
(It MIGHT possibly help against Covid-19, but remember: this is not medical advice!, check everything & talk to your doctor!)
Beta-Interferon ist ein Glykoprotein aus der Familie der Interferone. Interferone sind Botenstoffe, die natürlich im Körper vorkommen.
Interferon beta wird von verschiedenen Zelltypen (zum Beispiel Fibroblasten und Makrophagen) produziert und sezerniert.
Interferon beta wird von verschiedenen Zelltypen (zum Beispiel Fibroblasten und Makrophagen) produziert und sezerniert.
deutsche Wikipediaseite für Beta-Interferon:
https://de.wikipedia.org/wiki/Beta-Interferon
Interferon-beta bei http://doccheck.com : https://flexikon.doccheck.com/de/Interferon-beta
https://de.wikipedia.org/wiki/Beta-Interferon
Interferon-beta bei http://doccheck.com : https://flexikon.doccheck.com/de/Interferon-beta
until now it looked like interferon-beta doesn't help ...
Here is an article & a long quote that puts the results into context:
1/3:
Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments
Published on October 16, 2020 https://www.sciencemag.org/news/2020/10/remdesivir-and-interferon-fall-flat-who-s-megastudy-covid-19-treatments
Here is an article & a long quote that puts the results into context:
1/3:
Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments
Published on October 16, 2020 https://www.sciencemag.org/news/2020/10/remdesivir-and-interferon-fall-flat-who-s-megastudy-covid-19-treatments
2/3:
Quote:
"[...] Solidarity’s “most disappointing results,” however, are those for interferon-beta, Topol says. Mortality among the 2050 people who received that drug (either alone or in combination with lopinavir/ritonavir) was 11.9%, versus 10.5% in the control group. [...]
Quote:
"[...] Solidarity’s “most disappointing results,” however, are those for interferon-beta, Topol says. Mortality among the 2050 people who received that drug (either alone or in combination with lopinavir/ritonavir) was 11.9%, versus 10.5% in the control group. [...]
3/3:
[...] Prior studies have suggested interferon can only help if given early, however, and not once patients have been hospitalized. “So I think that’s still an open question,” Topol says. [...]"
[...] Prior studies have suggested interferon can only help if given early, however, and not once patients have been hospitalized. “So I think that’s still an open question,” Topol says. [...]"
now we have new promising results that challenge the former findings:
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial
Nov 12
Study
https://thelancet.com/journals/lanres/article/PIIS2213-2600(20)30511-7/fulltext
comment 1:
https://twitter.com/EricTopol/status/1327031414273970176
comment 2: https://twitter.com/ABsteward/status/1327036140382203904
Nov 12
Study
https://thelancet.com/journals/lanres/article/PIIS2213-2600(20)30511-7/fulltext
comment 1:
https://twitter.com/EricTopol/status/1327031414273970176
comment 2: https://twitter.com/ABsteward/status/1327036140382203904
Interferon beta and alpha are very similar, and are believed to have evolved following a gene duplication event.
Interferon beta-1a is suspected to be more effective than alpha-2b against Coronaviruses and certain other viruses.
Thread https://twitter.com/__ice9/status/1281398349040701441
Interferon beta-1a is suspected to be more effective than alpha-2b against Coronaviruses and certain other viruses.
Thread https://twitter.com/__ice9/status/1281398349040701441
relevant Thread with Sub-Threads from July 2020 https://twitter.com/__ice9/status/1285282711293263875
another great Thread with important Sub-Threads from July 2020
.... so much was missed by so many .... https://twitter.com/__ice9/status/1285292216269918210
.... so much was missed by so many .... https://twitter.com/__ice9/status/1285292216269918210
one of the tweets from the Thread https://twitter.com/__ice9/status/1285307668521984009
