1/ There is a confusion between early vs advanced cancer & Superficial vs Deep Ca
👉 Early Ca-Invasion depth to submucosa only, irrespective of nodal status
👉 Advanced Ca- invasion beyond submucosa with regional nodes or distant metastasis
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2/ Superficial lesions- those that are believed to be endoscopically resectable

Deep lesions- those that are deemed “too deep” to be scooped, and thus endoscopically unresectable

#GIFellows #ACG #Tweetorial
3/ The decision for endoscopic resection is based on combination of morphological and advanced imaging appearance (NBI/Chromo) @giendo_roy

High Risk for Submucosal Invasion
👎 Depressed lesion
👎 Kudo V pit pattern
👎 NICE 3 pattern
👎 Fold convergence
👎 Non-lifting sign
4/After endoscopic treatment, curative or non-curative resection is established based on histology

Curative cut
👍Well or mod differentiated
👍Good lateral margins (>1mm)
👍Confined to superficial submucosa (<1mm)(Level3 in polypoid lesion)
👍No LV involvement
👍No tumor budding
5/There are numerous facts that we use reflexively when assessing the malignant potential of a polyp. At times, a single finding is enough to diagnose SM invasion. Other times, combination two or more findings needed for diagnosis.
How we use these information in decision making
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