The reason COVID19 is so deadly is because our immune system has never seen it before. 8% of true human genome consists of viruses contracted by our ancestors which is why we have so immunity to most viruses (and more of you’re vaccinated.) Whenever a pathogen enters the body,
Part of the primary response is the release of cytokines. These are chemicals which stimulate and regulate cell pathways (they basically tell them what to do and how they should act.) With a novel virus, the code which all pathogens contain (PAMP) allows leukocytes to respond to
The invasion but the response is non specific-that comes later.
The theory is that there is an acceleration of cytokine production. Whilst some is helpful, too much interrupts normal cell function. This has an especially profound effect on inflammation.
Think of it like getting
Your foot stuck on the accelerator. Treatments work by slowing down the inflammatory response and allowing cell function to return to normal, however this takes time. COVID19 patients require long periods of high pressure ventilation and medications such as dexamethasone, whilst
Helpful, have side effects of their own.
So when we see mortality rates, what is not shown is morbidity rates. COVID19 is creating a new generation of people with underlying health conditions who will require NHS services. The long term effects of the pandemic will continue to
Unveil themselves over the coming years. When the general public will be getting back to some semblance of normal, medics will still be dealing with the aftermath.
I have no idea where the word true came from 😳
You can follow @pleased2bme.
Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled:

By continuing to use the site, you are consenting to the use of cookies as explained in our Cookie Policy to improve your experience.