Some of the new Bioconductor packages that caught my eye. There are way more great new contributions than I can cover, do check the full list here for your topics of interest:

http://bioconductor.org/news/bioc_3_12_release/ https://twitter.com/mikelove/status/1323247834871795714

bambu from @chenyin76951822 Yuk Kei Wan @JonathanGoeke

multi-sample transcript discovery and quantification using long read RNA-Seq data

http://bioconductor.org/packages/release/bioc/html/bambu.html

biocthis from @lcolladotor and @M2RUseR

expands the usethis package with the goal of helping automate the process of creating R packages for Bioconductor

http://bioconductor.org/packages/release/bioc/html/biocthis.html

marr from Katerina Kechris and @ghoshd groups

nonparametric approach that detects reproducible signals using a maximal rank statistic for high-dimensional biological data

http://bioconductor.org/packages/release/bioc/html/marr.html

MOFA2, sequel to MOFA, from @RArgelaguet @BrittaVelten and Damien Arnol, Danila Bredikhin

http://bioconductor.org/packages/release/bioc/html/MOFA2.html

musicatk from Chevalier and Campbell

flexible framework to allow users to mix and match different types of mutations in the mutational signature inference process

http://bioconductor.org/packages/release/bioc/html/musicatk.html

pipeComp from @GermainPl @AnthonySonrel @markrobinsonca

facilitate the comparison of pipelines involving various steps and parameters

http://bioconductor.org/packages/release/bioc/html/pipeComp.html

recount3 from @lcolladotor

recountmethylation from Maden, Thompson, @KasperDHansen @AbhiNellore

great compilation datasets, ready to analyze in Bioc

http://bioconductor.org/packages/release/bioc/html/recount3.html

http://bioconductor.org/packages/release/bioc/html/recountmethylation.html

SpatialExperiment from @drighelli @drisso1893

Bioc S4 classes for storing data for spatial experiments

http://bioconductor.org/packages/release/bioc/html/SpatialExperiment.html

velociraptor (i know that's a T-Rex...) from @KevinRUE67 Aaron Lun @CSoneson

Bioconductor-friendly wrappers for RNA velocity calculations in single-cell RNA-seq data

http://bioconductor.org/packages/release/bioc/html/velociraptor.html

And online books now on the Bioconductor builders, both OSCA (too many authors to name!) and SingleR (Aaron Lun). These are excellent resources!