[1/7] Absolutely chuffed about @joybergelson’s, Fabrice Roux’ and my lab’s #PATHOCOM project selected for funding by #ERCSyG @ERC_Research program. Our full project proposal at https://doi.org/10.6084/m9.figshare.13174337, and briefly explained in this thread.
[2/7] Co-infection is often the key predictor of disease outcome. E.g., the majority of deaths during the 1918/1919 flu pandemic were caused by complications from bacterial pneumonia https://pubmed.ncbi.nlm.nih.gov/18710327/
[3/7] The same is true in Arabidopsis, where we have found evidence for synergism and cooperation among #pathogen|s https://www.nature.com/articles/s41396-018-0152-7. In #PATHOCOM, we want to understand how cooperation allows pathogens to overtake #microbial communities inside a host and cause #disease.
[4/7] #PATHOCOM will integrate large-scale field observations, ultra-hi throughput infxs in the lab, field expts with #GMO in the US & sophisticated modeling. Informed by ecological & genetic knowledge, we hope to extrapolate from local interactions to community-level patterns.
[5/7] #PATHOCOM aims to reveal key ecological & genetic drivers of pathogen success. The ultimate goal is to help transform #plant- #pathogen- #microbiome studies into a predictive science.
[6/7] The synergy between experiment & theory, #ecology & #genomics, quantitative genetics & molecular biology will allow us to address the dynamics of #microbial #pathogens in & on #plants under lab & natural conditions.
[7/7] Curious? Interested in joining us? We’ll soon start recruiting students, postdocs, engineers & technicians for #PATHOCOM. Read the full proposal https://doi.org/10.6084/m9.figshare.13174337 and let us know how you might fit in. #PlantSciJobs