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1/11 I think that the most important piece of research since 2017 about putting #type2diabetes into remission was published today in @BMJNutrition
The results are simply astonishing
A twitter thread.... #MedTwitter #LCHF
Here's the paper
https://nutrition.bmj.com/content/early/2020/10/21/bmjnph-2020-000072
The results are simply astonishing
A twitter thread.... #MedTwitter #LCHF
Here's the paper
https://nutrition.bmj.com/content/early/2020/10/21/bmjnph-2020-000072
2/11 The study is by @lowcarbGP @jen_unwin + others and looks at reversing T2DM and pre-diabetes by lifestyle change, in particular by 
sugar and starchy carbs
sugar and starchy carbs
3/11 The study builds on the work of Prof Roy Taylor's DiRECT Study which found that *severe* calorie restriction could put T2DM into remission
More info here
https://www.directclinicaltrial.org.uk/
This was great news but SO many people find calorie restriction IMPOSSIBLE TO SUSTAIN
More info here
https://www.directclinicaltrial.org.uk/
This was great news but SO many people find calorie restriction IMPOSSIBLE TO SUSTAIN
4/11 The study:
Carried out in "real-world primary care" in a *normal* #NHS GP surgery in
128 people with T2DM and 71 with pre-diabetes volunteered to try a lower carbohydrate diet for an average of 23 months #LCHF
Some have been on it for 6 years (and counting !)
Carried out in "real-world primary care" in a *normal* #NHS GP surgery in
128 people with T2DM and 71 with pre-diabetes volunteered to try a lower carbohydrate diet for an average of 23 months #LCHF
Some have been on it for 6 years (and counting !)
5/11 People were supported with normal 10 min GP appointments + some group consultations
A simple information sheet with basic advice on reducing carbs was given out
You can download it here
https://nutrition.bmj.com/content/bmjnph/early/2020/10/21/bmjnph-2020-000072/F1.large.jpg
A simple information sheet with basic advice on reducing carbs was given out
You can download it here
https://nutrition.bmj.com/content/bmjnph/early/2020/10/21/bmjnph-2020-000072/F1.large.jpg
6/11 Excellent infographics about how sugary common foods are were given out as well
You can find them here https://phcuk.org/sugar/
You can find them here
https://phcuk.org/sugar/
7/11 THE RESULTS
In people with T2DM:
46% achieved drug-free remission of their diabetes. WOW!!
Ave in HbA1c was 17.5mmol/mol 
93% of those with pre-diabetes achieved remission
But that's not all....
In people with T2DM:
46% achieved drug-free remission of their diabetes. WOW!!
Ave
in HbA1c was 17.5mmol/mol 93% of those with pre-diabetes achieved remission
But that's not all....
8/11
- Average BP11/5mmHg so some BP meds could be stopped
- Improvements in total and LDL cholesterol
- triglycerides
- Average weight 8.3kg
BUT weight correlated poorly with improvements in diabetes control
- Average BP
11/5mmHg so some BP meds could be stopped- Improvements in total and LDL cholesterol
-
triglycerides - Average weight
8.3kg BUT weight
correlated poorly with improvements in diabetes control
9/11 Of course, many medications for diabetes and BP could be stopped meaning that Norwood Surgery saves over £50k EACH YEAR on diabetes meds compared to local practices
Imagine how much money could be saved if practices across theand the 
did this 
@DrAbdulZubairu
Imagine how much money could be saved if practices across the
and the did this @DrAbdulZubairu
10/11 Conclusions:
ing sugar + starchy carbs delivers a real possibility of:
- Reversing T2DM + pre-diabetes
- Improved BP and cholesterol
- An effective solution sustainable for years (unlike severe calorie reduction)
Benefits ofing carbs are INDEPENDENT of weight loss
ing sugar + starchy carbs delivers a real possibility of:- Reversing T2DM + pre-diabetes
- Improved BP and cholesterol
- An effective solution sustainable for years (unlike severe calorie reduction)
Benefits of
ing carbs are INDEPENDENT of weight loss
11/11 Declaration of interest
This surgery is my own practice, Norwood Surgery in Southport. I'm so proud of what we've achieved. It's been a huge pleasure + privilege to to be a small part of this research led by my inspirational friend, trail-blazer + mentor @lowcarbGP
This surgery is my own practice, Norwood Surgery in Southport. I'm so proud of what we've achieved. It's been a huge pleasure + privilege to to be a small part of this research led by my inspirational friend, trail-blazer + mentor @lowcarbGP
