1/11 I think that the most important piece of research since 2017 about putting #type2diabetes into remission was published today in @BMJNutrition

The results are simply astonishing

A twitter thread.... #MedTwitter #LCHF

Here's the paper

https://nutrition.bmj.com/content/early/2020/10/21/bmjnph-2020-000072

2/11 The study is by @lowcarbGP @jen_unwin + others and looks at reversing T2DM and pre-diabetes by lifestyle change, in particular by sugar and starchy carbs

3/11 The study builds on the work of Prof Roy Taylor's DiRECT Study which found that *severe* calorie restriction could put T2DM into remission
More info here
https://www.directclinicaltrial.org.uk/ 

This was great news but SO many people find calorie restriction IMPOSSIBLE TO SUSTAIN

4/11 The study:

Carried out in "real-world primary care" in a *normal* #NHS GP surgery in
128 people with T2DM and 71 with pre-diabetes volunteered to try a lower carbohydrate diet for an average of 23 months #LCHF
Some have been on it for 6 years (and counting !)

5/11 People were supported with normal 10 min GP appointments + some group consultations

A simple information sheet with basic advice on reducing carbs was given out

You can download it here
https://nutrition.bmj.com/content/bmjnph/early/2020/10/21/bmjnph-2020-000072/F1.large.jpg

6/11 Excellent infographics about how sugary common foods are were given out as well

You can find them here https://phcuk.org/sugar/ 

7/11 THE RESULTS

In people with T2DM:

46% achieved drug-free remission of their diabetes. WOW!!
Ave in HbA1c was 17.5mmol/mol

93% of those with pre-diabetes achieved remission

But that's not all....

8/11

- Average BP 11/5mmHg so some BP meds could be stopped
- Improvements in total and LDL cholesterol
- triglycerides
- Average weight 8.3kg

BUT weight correlated poorly with improvements in diabetes control

9/11 Of course, many medications for diabetes and BP could be stopped meaning that Norwood Surgery saves over £50k EACH YEAR on diabetes meds compared to local practices

Imagine how much money could be saved if practices across theand the did this

@DrAbdulZubairu

10/11 Conclusions:

ing sugar + starchy carbs delivers a real possibility of:

- Reversing T2DM + pre-diabetes
- Improved BP and cholesterol
- An effective solution sustainable for years (unlike severe calorie reduction)

Benefits of ing carbs are INDEPENDENT of weight loss

11/11 Declaration of interest

This surgery is my own practice, Norwood Surgery in Southport. I'm so proud of what we've achieved. It's been a huge pleasure + privilege to to be a small part of this research led by my inspirational friend, trail-blazer + mentor @lowcarbGP