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Bio is a general purpose technology (GTP) for the 6th technology revolution, following past 5 successive technology revolutions since 1771. 2021 marks the start of the 6th technology revolution. Each technology revolution introduced a techno-economic paradigm powered by a GTP...
...e.g. water mills, steam engine, electricity, combustion engine, ICT, and now, bio-nano-intelligence.
Bio approaches the end of installation phase technology cycle, proceeds to deployment phase where we'll see orders of more pervasive and novel applications to all areas of humanity from now to 20-30 years. @karpathy @jackclarkSF
https://www.nature.com/articles/s41467-020-19092-2#ref-CR9
https://www.nature.com/articles/s41467-020-19092-2#ref-CR9
The bio generality and novelty is made possible by the universality of DNA that serves as a universal 'life toolkit' (see universality definition in Beginning of Infinity by Deutsch). Understanding the nature of the universality of the DNA system is central to bio to achieve...
...artificial evolution/creativity of living mechanisms/organisms, as well as regeneration of life and biosphere to become a spacefaring, spaceliving species. @DavidDeutschOxf @naval
Universality of DNA system includes:
1) Genome
2) Epigenome
3) Circuitry
4) Patterns of convergence from genetic variants to biological processes.
- Multiple genetic variants (distributed across people) → same enhancer
- Multiple enhancers → same gene
1) Genome
2) Epigenome
3) Circuitry
4) Patterns of convergence from genetic variants to biological processes.
- Multiple genetic variants (distributed across people) → same enhancer
- Multiple enhancers → same gene
...
- Multiple genes → same pathway (e.g. calcium signaling)
- Multiple pathways → same tissue
- Multiple tissues → same biological process (e.g. schizophrenia)
https://twitter.com/lexfridman/status/1320506274015027202?s=20
@manoliskellis @lexfridman
- Multiple genes → same pathway (e.g. calcium signaling)
- Multiple pathways → same tissue
- Multiple tissues → same biological process (e.g. schizophrenia)
https://twitter.com/lexfridman/status/1320506274015027202?s=20
@manoliskellis @lexfridman
These universalities enable infinite space of possibilities, massive parallel experimentation, directional and convergent bio research, and general unified theory of bio—ageing, diseases, bio-design platforms etc.
Bio is advanced nanotechnology to program matter for marveling life functions and forms. Cultivate vast 'space of the possible' through artificial evolution, artificial creativity.
https://a16z.com/2020/10/13/nielsen-biology-engineering-design-tools/
@vijaypande @alectricity
https://a16z.com/2020/10/13/nielsen-biology-engineering-design-tools/
@vijaypande @alectricity
