This study is getting a lot of attention, but I’m not sure if people are reading it.
There is no guarantee these household contacts didn’t get infection at same time, and one just has symptoms before the other. It’s a huge limitation. https://twitter.com/drtomfrieden/status/1322570327734497285
There is no guarantee these household contacts didn’t get infection at same time, and one just has symptoms before the other. It’s a huge limitation. https://twitter.com/drtomfrieden/status/1322570327734497285
The first sentence in limitations:
“First, the initial household member who experienced symptoms was considered the index patient, but it is possible that other household members were infected concurrently but developed symptoms at different times or remained asymptomatic.”
“First, the initial household member who experienced symptoms was considered the index patient, but it is possible that other household members were infected concurrently but developed symptoms at different times or remained asymptomatic.”
In a key sensitivity analysis, excluding 54 household members who had SARS-CoV-2 detected in specimens taken *at enrollment,* the secondary infection rate was 35%, without a breakdown by age of index case.
It is the job of experts to communicate uncertainty when it exists.
It is the job of experts to communicate uncertainty when it exists.