Thread by @TristanRutland7, Older patient, lung mass.@ZHOUSEH @MattieFarzin @smlungpathguy @quadrellis #pulmpath #liverpoolpath #aussiepath #surgpath #PathTwitter [...]

Tristan D Rutland

TristanRutland7

Older patient, lung mass.

@ZHOUSEH @MattieFarzin @smlungpathguy @quadrellis

#pulmpath #liverpoolpath #aussiepath #surgpath #PathTwitter

Congo red.

Diagnosis:

Corpora Amylacea on a background of organising pneumonia.

Learning points:

1) CA can be positive for Congo red! They are actually thought to contain amyloid protein. https://pubmed.ncbi.nlm.nih.gov/1385482/

Amyloid in prostatic corpora amylacea - PubMed

Prostatic corpora amylacea represents a localised amyloidosis of beta 2 microglobulin origin that is unrelated to chronic renal failure and haemodialysis.

https://pubmed.ncbi.nlm.nih.gov/1385482/

2) Originally called corpora colloidea they were first described in the prostate back in 1727 by Morgagni (yes that one). After that, they were described in other sites (including Lung). As I love medical history

https://jamanetwork.com/journals/jama/article-abstract/454066

THE ORIGIN OF CORPORA AMYLACEA IN THE PROSTATE GLAND.

The formations designated by Seigert as corpora colloidea, and commonly known as corpora amylacea, have been observed in various organs. Morgagni saw them first in the prostate gland in 1723. Virchow...

https://jamanetwork.com/journals/jama/article-abstract/454066

You can follow @TristanRutland7.

Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled: