Thread by @Mareq16, Hydroxychloroquine Thread1Chloroquine is a potent inhibitor of SARS coronavirus infection and spreadhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/ [...]

Hydroxychloroquine Thread

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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.We report, however, that...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/

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Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An Observational Study , https://www.preprints.org/manuscript/202005.0057/v1

Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An...

Background: There is no treatment proven effective against COVID-19. Several drugs with in vitro potential against SARS-CoV-2 virus have been proposed. Hydroxychloroquine has in vitro anti-viral and...

https://www.preprints.org/manuscript/202005.0057/v1

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Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France https://www.sciencedirect.com/science/article/pii/S1477893920302179 ,

Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective...

In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19.We retrospectively report on 1061 SARS-…

https://www.sciencedirect.com/science/article/pii/S1477893920302179

3.1 archive http://archive.is/VEdFi

Full-length title: Early treatment of COVID-19 patients with hydroxyc…

archived 6 May 2020 14:08:25 UTC

http://archive.is/VEdFi

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Chloroquine and hydroxychloroquine as inhibitors of human immunodeficiency virus (HIV-1) activity. https://www.ncbi.nlm.nih.gov/pubmed/15320751

Chloroquine and hydroxychloroquine as inhibitors of human immunodeficiency virus (HIV-1) activity -...

Recent advances in the development of antiretrovirals have significantly extended life-spans and positively impacted morbidity of HIV-seropositive patients. While effective, antiretrovirals are...

https://www.ncbi.nlm.nih.gov/pubmed/15320751

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Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689966/

Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regula...

The burden of obesity and associated cardiometabolic diseases has been considered as an important risk factor for lupus patients. Therefore, whether obesity is involved in the over-activation of...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689966/

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Chloroquine Is a Zinc Ionophore https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/

Chloroquine Is a Zinc Ionophore

Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/

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Chloroquine and hydroxychloroquine are associated with reduced cardiovascular risk: a systematic review and meta-analysis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001837/

Chloroquine and hydroxychloroquine are associated with reduced cardiovascular risk: a systematic...

Chloroquine (CQ) and hydroxychloroquine (HCQ) are widely used in patients with rheumatic diseases, but their effects on the cardiovascular system remain unclear. We aimed to assess whether CQ/HCQ...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001837/

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Drug Des Devel Ther. 2018; 12: 1685–1695, Published online 2018 Jun 11. doi: 10.2147/DDDT.S166893 https://pubmed.ncbi.nlm.nih.gov/16115318/

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread - PubMed

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after...

https://pubmed.ncbi.nlm.nih.gov/16115318/

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Chloroquine Is a Potent Inhibitor of SARS Coronavirus Infection and Spread
Here's the new study incoming: https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-hydroxychloroquine-azithromycin-treat-covid-19

NIH begins clinical trial of hydroxychloroquine and azithromycin to

Study enrolling adults with mild to moderate COVID-19 in the United States.

https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-hydroxychloroquine-azithromycin-treat-covid-19

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NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19

To keep track of the study, look here: https://clinicaltrials.gov/ct2/show/NCT04358068

Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death...

Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19 - Full Text View.

https://clinicaltrials.gov/ct2/show/NCT04358068

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Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19
Collaborator: Teva Pharmaceuticals Industries LTD https://www.ncbi.nlm.nih.gov/pubmed/16115318

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread - PubMed

https://www.ncbi.nlm.nih.gov/pubmed/16115318

11.1

...and https://www.ncbi.nlm.nih.gov/pubmed/15351731

In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine - PubMed

We report on chloroquine, a 4-amino-quinoline, as an effective inhibitor of the replication of the severe acute respiratory syndrome coronavirus (SARS-CoV) in vitro. Chloroquine is a clinically...

https://www.ncbi.nlm.nih.gov/pubmed/15351731

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Hydroxychloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant women and nursing mothers.

https://www.cdc.gov/malaria/resources/pdf/fsp/drugs/hydroxychloroquine.pdf

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Hydroxychloroquine as anti cancer agent

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718030/

https://archive.is/kQq0o

Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents

Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the treatment of cancer. Overall,...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718030/

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google doc detailed summary https://docs.google.com/document/d/1545C_dJWMIAgqeLEsfo2U8Kq5WprDuARXrJl6N1aDjY/preview

3.0 HCQ Lit-PD-HGS77X2-DC79

Sequential CQ / HCQ Research Papers and Reports January to April 20, 2020 Executive Summary Interpretation of the Data In This Report The HCQ-AZ combination, when started immediately after diagnosis,...

https://docs.google.com/document/d/1545C_dJWMIAgqeLEsfo2U8Kq5WprDuARXrJl6N1aDjY/preview

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Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718030/
https://archive.is/kQq0o

Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents

Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the treatment of cancer. Overall,...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718030/

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Sauce: https://c19study.com/

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Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals https://arthritis-research.biomedcentral.com/articles/10.1186/ar3868

Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals

Hydroxychloroquine (HCQ) is a common disease modifying therapy for the treatment of rheumatoid arthritis (RA). Prior research suggests that HCQ may reduce the risk of diabetes mellitus in patients...

https://arthritis-research.biomedcentral.com/articles/10.1186/ar3868

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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available. We report, however, that...

https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69

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Results We found a significant reduction in all-cause mortality and cardiovascular related death among HCQ initiators, with a hazard ratio of 0.83 (95% confidence interval [CI] 0.71–0.97) and 0.78 (95% CI: 0.61 to 0.99), respectively.

Sauce: https://ard.bmj.com/content/77/Suppl_2/144.3

OP0191 All-cause mortality and cardiovascular death in hydroxychloroquine users in rheumatoid...

Background Rheumatoid arthritis (RA) is associated with a marked increase in cardiovascular comorbidity and mortality(.1 The increased risk is present from the earliest stages of the disease and...

https://ard.bmj.com/content/77/Suppl_2/144.3

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Who can take hydroxychloroquine?
Hydroxychloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant women and nursing mothers.

Sauce...

https://www.cdc.gov/malaria/resources/pdf/fsp/drugs/Hydroxychloroquine.pdf

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Two articles.... https://twitter.com/Mareq16/status/1288761308406525952?s=19

https://twitter.com/Mareq16/status/1288761308406525952?s=19

https://twitter.com/Mareq16/status/1288399517742661637?s=19

https://twitter.com/Mareq16/status/1288399517742661637?s=19

23 https://twitter.com/Mareq16/status/1288104079781064706?s=19

https://twitter.com/Mareq16/status/1288104079781064706?s=19

Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford Health System Study Shows

https://www.henryford.com/news/2020/07/hydro-treatment-study

HT @AustIndiePress

Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford...

https://www.henryford.com/news/2020/07/hydro-treatment-study

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