If you don't want more 'Karens' refusing to wear masks, respect borders or whatever else, don't give them media attention. They're after validation & attention, starve them of both. No press, no comments, no tweets, no likes. Rage still = attention, still some form of validation.
When 'Karen from Brighton' leverages the attention for an Instagram account with 10k+ followers, you know attention-hungry pandemic conspiracy theorists are gunning for the same and more. https://www.news.com.au/lifestyle/real-life/news-life/coronavirus-karen-from-brighton-has-started-her-own-instagram-to-hit-back-at-haters/news-story/6145d83e5509c9c8b2ed6568d13d445d#.axssm
When a 'Karen in Bunnings' is on national television refusing to wear a mask while shopping, with every word broadcast, others will follow. No attention won't stop the lone individual, but it will certainly minimise the creation of more.