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Convalescent plasma treatment for SARS-CoV-2
infection
-most make antibody (Ab)
, most Ab neutralises (NAb) SARS-CoV-2 and most people retain measurable levels after 50 days
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.28.2001260?emailalert=true
infection
-most make antibody (Ab)
, most Ab neutralises (NAb) SARS-CoV-2 and most people retain measurable levels after 50 dayshttps://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.28.2001260?emailalert=true
Yes, there is a statistically significant drop in Ab and NAb levels over that time, but we don't know if that's a *biologically* significant drop.
Also cool, the authors, who have previously used these methods (they put *this* manuscript out as a preprint in May btw), noted that in their hands, the commercial Ab test could serve as a surrogate for eth more complex NAb test
FWIW-& I stand to be corrected-this is really good, not bad, news. Most people *do* mount a useful immune response.
We know from other studies that T cells are involved & it's likely, if SARS-CoV (1) was anything to go by, they drive lasting immune memory (yes, evidence needed)
We know from other studies that T cells are involved & it's likely, if SARS-CoV (1) was anything to go by, they drive lasting immune memory (yes, evidence needed)
The study also showed that *thinking* you had had COVID-19 was often wrong. Lab testing was required.
I'd like to compare studies of *other* viruses where this same sort of analysis was done.
Any immunologists-you wizards of the science world (or @HarvalaHeli; nice work btw) - who could link me to some studies that have done these kinds of studies on other viruses?
Any immunologists-you wizards of the science world (or @HarvalaHeli; nice work btw) - who could link me to some studies that have done these kinds of studies on other viruses?
