A collection of threads on susceptibility and possibility of prior cross reactive immunity to COVID for those interested.

1) I wondered in March, whether there is innate, cross reactive immunity to COVID because I was totally puzzled by what happened in Wuhan. https://twitter.com/vincentrk/status/1244347036293627910
Then it became more interesting when we look at same thing playing out in Lombardy and in NY, again raising the possibility that not everyone is susceptible either coz of cross reactive immune response (?prior other corona virus infections, childhood vaccines) or generic factors https://twitter.com/vincentrk/status/1274792133929639936
The way COVID played out in other hotspots lent more support to this idea. https://twitter.com/vincentrk/status/1276159410264576000
Now we have supporting laboratory data of T cells reactive to COVID present in samples before the onset of COVID indicating that cross reactive immune responses are possible and why some proportion of the population may not be fully susceptible to COVID. https://twitter.com/vincentrk/status/1278017849781563394?s=21 https://twitter.com/vincentrk/status/1278017849781563394
The Antarctica cruise story also lends support to this idea, being a natural experiment. https://twitter.com/vincentrk/status/1275838416236580867
My colleague @Rfonsi1 has a good thread summarizing what we know. https://twitter.com/rfonsi1/status/1277643561316388864
Here is a great thread by @ethanjweiss raising the same possibility last month based on cross reactive immunity from original SARS. https://twitter.com/ethanjweiss/status/1271069722751070208?s=21 https://twitter.com/ethanjweiss/status/1271069722751070208
You can follow @VincentRK.
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