Sweden's government is to the COVID-19 pandemic what South Africa's (Mbeki) government was to the AIDS pandemic
They ditched mainstream, evidence-based advice.
So their people died
https://link.springer.com/article/10.1007/s10461-009-9654-7
https://link.springer.com/content/pdf/10.1007/s10461-009-9641-z.pdf
https://twitter.com/AtomsksSanakan/status/1277378705028001801
http://archive.is/n2cvr
They ditched mainstream, evidence-based advice.
So their people died
https://link.springer.com/article/10.1007/s10461-009-9654-7
https://link.springer.com/content/pdf/10.1007/s10461-009-9641-z.pdf
https://twitter.com/AtomsksSanakan/status/1277378705028001801
http://archive.is/n2cvr
Finding T cells with (supposed) seronegativity is an issue when:
1) Antibody test's sensitivity isn't stated
https://web.archive.org/web/20200702064515/https://www.biorxiv.org/content/10.1101/2020.06.29.174888v1
https://www.nature.com/articles/s41591-020-0965-6?fbclid=IwAR1TsBPC9LaTFgzJC6a90y6WtaiZe4D4L4nRmKaYeB2jGCu-1eAYBsaD8JA
2) COVID-19 often involves pathological, immune-mediated cytokine storm
http://archive.is/ISw5W#selection-20053.0-20131.115
1) Antibody test's sensitivity isn't stated
https://web.archive.org/web/20200702064515/https://www.biorxiv.org/content/10.1101/2020.06.29.174888v1
https://www.nature.com/articles/s41591-020-0965-6?fbclid=IwAR1TsBPC9LaTFgzJC6a90y6WtaiZe4D4L4nRmKaYeB2jGCu-1eAYBsaD8JA
2) COVID-19 often involves pathological, immune-mediated cytokine storm
http://archive.is/ISw5W#selection-20053.0-20131.115
Re: "1) Antibody test's sensitivity isn't stated"
So if sensitivity is low, many of their seronegatives are false negatives. That's especially an issue if their studied population's proportion of true seronegatives was also low.
https://twitter.com/GidMK/status/1278468845615738880
https://www.bmj.com/content/370/bmj.m2516
So if sensitivity is low, many of their seronegatives are false negatives. That's especially an issue if their studied population's proportion of true seronegatives was also low.
https://twitter.com/GidMK/status/1278468845615738880
https://www.bmj.com/content/370/bmj.m2516
Re: "2)"
So finding T cells doesn't entail Sweden was closer to herd immunity, despite what's said by some non-experts who distort medical science to justifying their ideological opposition to lockdowns
https://reason.com/2020/07/01/covid-19-herd-immunity-is-much-closer-than-antibody-tests-suggest-say-2-new-studies/
https://www.dailymail.co.uk/news/article-8477309/Publics-immunity-coronavirus-twice-high-believed.html
https://www.the-sun.com/news/1064559/coronavirus-immunity-twice-high-antibody-tests-suggest/
So finding T cells doesn't entail Sweden was closer to herd immunity, despite what's said by some non-experts who distort medical science to justifying their ideological opposition to lockdowns
https://reason.com/2020/07/01/covid-19-herd-immunity-is-much-closer-than-antibody-tests-suggest-say-2-new-studies/
https://www.dailymail.co.uk/news/article-8477309/Publics-immunity-coronavirus-twice-high-believed.html
https://www.the-sun.com/news/1064559/coronavirus-immunity-twice-high-antibody-tests-suggest/
Re: "Finding T cells with (supposed) seronegativity is an issue when:
1) Antibody test's sensitivity isn't stated"
An illustration of the point that finding no antibodies can be due to one's test having low sensitivity, not a lack of antibodies:
https://www.medrxiv.org/content/10.1101/2020.07.11.20151324v1.full.pdf
1) Antibody test's sensitivity isn't stated"
An illustration of the point that finding no antibodies can be due to one's test having low sensitivity, not a lack of antibodies:
https://www.medrxiv.org/content/10.1101/2020.07.11.20151324v1.full.pdf
Re: "So finding T cells doesn't entail Sweden was closer to herd immunity"
Another illustration of the point (h/t to @EuphoricEuler):
https://threadreaderapp.com/thread/1280943933569200128.html https://twitter.com/profshanecrotty/status/1280944124267393024
Another illustration of the point (h/t to @EuphoricEuler):
https://threadreaderapp.com/thread/1280943933569200128.html https://twitter.com/profshanecrotty/status/1280944124267393024
Re: "(supposed) seronegativity"
Studies with smaller sizes, showing antibodies either not appearing in some patients and/or falling beneath limit of detection by ~3 months:
https://web.archive.org/web/20200625074457/https://www.medrxiv.org/content/10.1101/2020.03.24.20042382v1.full.pdf
https://www.biorxiv.org/content/10.1101/2020.07.16.206847v1.full.pdf
Large study showing otherwise:
https://web.archive.org/web/20200720222438/https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1.full.pdf
Studies with smaller sizes, showing antibodies either not appearing in some patients and/or falling beneath limit of detection by ~3 months:
https://web.archive.org/web/20200625074457/https://www.medrxiv.org/content/10.1101/2020.03.24.20042382v1.full.pdf
https://www.biorxiv.org/content/10.1101/2020.07.16.206847v1.full.pdf
Large study showing otherwise:
https://web.archive.org/web/20200720222438/https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1.full.pdf
Re: "Antibody test's sensitivity isn't stated"
A great thread giving some ore context on this, except less focus on test sensitivity and more focused on the immunology 101 behind natural drops in antibody levels (that don't fall below limits of detectio)
https://twitter.com/florian_krammer/status/1285654615392948225
A great thread giving some ore context on this, except less focus on test sensitivity and more focused on the immunology 101 behind natural drops in antibody levels (that don't fall below limits of detectio)
https://twitter.com/florian_krammer/status/1285654615392948225