Shall we change the name from #NAFLD ➡️MAFLD?
Two recent international consensus statements in Gastro and J Hep say so.
I believe I was first to suggest this "new" name in a Gastro paper in 2005!
Anyone knows earlier reference so I stop gloating?
But...
Why "Metabolic Fatty Liver Disease"?
Evidence in that 2005 Gastro paper still rings true:
1⃣ Should be "Metabolic" because metabolic syndrome, insulin resistance and obesity are contributors
2⃣ Should not be "nonalcoholic" ➡️ it also occurs in etoh, hcv etc
Not much new evidence presented in the two recent consensus statements proposing MAFLD/MASH
With the benefit of the last 15 yrs, can we do better than MAFLD and MASH?
Should the name reflect the etiologic factor that causes progression to cirrhosis and HCC?
What is the equivalent of "alcohol" in NAFLD?
Ready to propose a different name!!
I think this Hepatology article is a more nuanced: they think the change to MAFLD is "premature".
But Drs. Younossi, Rinella and Sanyal also co-authored the Statements recommending the change!
Guys what do you really think?
You can follow @gnioannou.
Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled:

By continuing to use the site, you are consenting to the use of cookies as explained in our Cookie Policy to improve your experience.