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Studied around 3 major medical research that Withanone (a compound) from Withania somnifera (Ashwagandha) has properties to Inhibit Novel Coronavirus (COVID-19) Entry by Disrupting Interactions between Viral S-Protein Receptor Binding Domain and Host ACE2 Receptor. Interesting 
A recent research conducted by the scientists at the IIT-Delhi has found that Ashwagandha contains certain bio-actives that interact with SARS-Co-2. This herb contains a natural compound called withanone (Wi-N), that can block the replication process of the novel virus & treat it
Even the Government of India has ordered Clinical reserach & trials of Ashwagandha & its compound Withanone in treatment of n-Cov2 or COVID-19. There is known research is on it how Indian Herb Ashwagandha helps treat various kinds diseases and human ailments.
More importantly, Ashwagandha plant has been reported for its potent antiviral activity against dif- ferent kinds of viruses such as H1N1 influenza, herpes simplex type-1, hepatitis, coxsackie virus, bursal disease virus, HIV, their infections & replications a study of 2018 showd
Tulsiâ has Traditionally been used for Protection from Infection. Tulsi has traditionally been used for it's anti-bacterial, anti-viral and anti-fungal properties. It is rich in Vitamin C & ZINC and thus acts as natural immunity booster. Zinc boosts T Cells from Bone Marrow.
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Giloyâ has strong antioxidant properties, which protects against free radical damage and boosts immunity. It helps in reducing fever, also effective for chronic fevers & boost blood platelets count. Giloy is even used in Dengue & Chikanguniya & its associated chronic fever.
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Ashwagandhaâ, improving immunity to reducing stress, regulating blood sugar level& lowering cholesterol, Ashwagandha does it all. The analgesic & antioxidant properties of the leaves of ashwagandha r used for treating a viral infection, cough & cold symptoms, fever & chronic pain
So the combination Tulsi, Ashwagandha & Giloy potent one as Immuno Booster as well as Anti Viral. However further studies are yet to establish the potency of Withanone compound of Ashwagandha on SARS-CoV2 with extensive clinical trials. END
Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach [31st May 2020] [Indian Ginseng = Ashwagandha] #Study https://www.tandfonline.com/doi/full/10.1080/07391102.2020.1778539?scroll=top&needAccess=true
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity [05th May 2020 #Study] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284143/
These are 2 clinical studies on Ashwagandha & its compound Withanone on prospective & preventive treatment for Sars-CoV2. This is in addition to Patanjali's manuscript released talking of similar findings. Shared the links two independent medical studies on it.
Patanjali working on similar formulation but what it did was it applied for the Drug as natural immunity booster, cough & fever while marketing it as COVID cure probably wanting to preempt others in market as applying for Drug as covid cure wud need more research, review & trial.
Anyways cutting the long story short. In market there are many formulations with Tulsi & Giloy with Wheat Grass available, add Ashwagandha too it to make it good immunity choice for you body in the season of Viral Flu.
This is patanjali's manuscript on use of Withanone in Ashwagandha for trials on SARS-CoV2 replication and binding process.
https://www.researchsquare.com/article/rs-17806/v1
https://www.researchsquare.com/article/rs-17806/v1
Shared all three studies in the above series of tweets. END
On the Inhibition of COVID-19 Protease by Indian Herbal Plants: An In Silico Investigation - Another 2020 study of various Indian Herbs and their effects on biding properties (Good read for understanding concept) https://arxiv.org/pdf/2004.03411.pdf
@threadreaderapp unroll
There are many Indian herbs that inhibit the binding & replication process but Ashwagandhaâs Withanone has taken the lead as per various detailed research done so far.
Ashwagandha takes the lead to be the mother natureâs COVID-19 warrior: IIT Delhi Study [Link] https://home.iitd.ac.in/news-covidaswagandha.php
