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Many asked me about dexamethasone today.
Sadly, another over-hyped "miracle" drug by certain fame-crazed doctors and science reporters.
the effectiveness of dexamethasone for *severe* COVID patients is neither surprising nor encouraging.
Sadly, another over-hyped "miracle" drug by certain fame-crazed doctors and science reporters.
the effectiveness of dexamethasone for *severe* COVID patients is neither surprising nor encouraging.
dexamethasone is a long-acting corticosteroid. like most corticosteroids, it reduces inflammation and suppresses immune response, both effects helpful to cope with a cytokine storm.
Other corticosteroids that have been used for COVID19 include methylprednisolone and prednisolone
Other corticosteroids that have been used for COVID19 include methylprednisolone and prednisolone
Using corticosteroids is nothing new, and has always been an option for severe COVID patients as well as for SARS/MERS patients years ago.
https://covidprotocols.org/protocols/therapeutics/#systemic-corticosteroids
This methylprednisolone paper was published in March (death rate cut by 2/3)
https://pubmed.ncbi.nlm.nih.gov/32167524/
https://covidprotocols.org/protocols/therapeutics/#systemic-corticosteroids
This methylprednisolone paper was published in March (death rate cut by 2/3)
https://pubmed.ncbi.nlm.nih.gov/32167524/
The problem with corticosteroids is its severe side effects: psychosis, diabetes, avascular necrosis (AVN).
My mom developed AVN in both hip joints after a course of corticosteroids, which is irreversible and requires hip replacement.
My mom developed AVN in both hip joints after a course of corticosteroids, which is irreversible and requires hip replacement.
But hyping dexamethasone as an everyday pill and a breakthrough for "anyone" with COVID is awful., even for the low-dosage (60mg total) used in this study.
Plus many of the dead UK patients was probably already on corticosteroids prior to their death.
Plus many of the dead UK patients was probably already on corticosteroids prior to their death.
