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#ACE2
Björn Meyer
_b_meyer
The mutation 501Y, which is present in both lineages from the UK (501Y.V1) and SA (501Y.V2) shows an increased affinity to the entry receptor Ace2. This was mainly known already.
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Eclecticity
twistopherrobin
This is a story about science… told by a non-scientist. It begins over twenty years ago when a team of researchers (including a physician/geneticist) was peering into the hearts of
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A.M.
bhalomanush
As we wait for vaccines, let’s not forget drugs. We still need effective drugs against SARS-CoV-2 (and other coronaviruses that will infect humans in the future).There is an approach that
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Eugene Ong
uginong
Summary of ‘Naturally mutated spike proteins of SARS-CoV-2 variants show 2 differential levels of cell entry’ preprint by Ozono et al., 2020. https://doi.org/10.1101/2020.06.15.151779Disclaimer: This summary is shared as a first-time
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Elinor Karlsson
eenork
Remember March, the endless month? That was the month that the #covid19 #pandemic became real, at least where I work @UMassMedical @broadinstitute. Suddenly we were working from home, and a
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Laurie Garrett
Laurie_Garrett
OK, some thoughts about noses and #SARSCoV2 infection. There is increasing epidemiological evidence that people who improperly wear masks -- not covering their noses -- or use face shields instead
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Björn Meyer
_b_meyer
Seeing that B1.1.7 now acquired the E484K mutation in the UK, could we, at least for now, stop the narrative that this double mutation occurs by high immune pressure, please?because
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Dr Zoë Hyde
DrZoeHyde
(1/14) Very important viral load & susceptibility study of 192 children (49 positive for #SARSCoV2, 18 with MIS-C, 125 negative).Despite having generally mild symptoms, children who tested positive had a
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ChristosArgyropoulos
ChristosArgyrop
I will consult my crystal ball and discuss some things that will become entirely apparent by the end of 2021 when the #COVID19 will either be entirely crashed or on
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Brian Wasik
BrianRWasik
Back in May, I was one of many that had a public conservative approach to assessing a variant... that may have seeded with lineages of our reference strain in many
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Dr. Urso
richardursomd
This covid crisis is focused on masks and distancing. We should be focused on prophylaxis with HCQ, (perhaps zinc and vitamin D) for front line workers and those at high
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Kai Kupferschmidt
kakape
It’s becoming clearer that one main hypothesis that scientists are looking at with B.1.1.7 is whether its advantage could be that it is better at infecting children. There are a
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Betsy Hakey Russell
betsy1954
In 2005 the US Army and DARPA began a process through which they started manipulating the corona virus using 2 different strains of corona virus amplifying pathogenicity of the virus.
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Bunsen and Beaker
bunsenbernerbmd
Have you heard about the “variants” of #COVID19 ?Let’s break it down!!!Yep- there are always variants of viruses out there. When they copy themselves they make mistakes and POW you
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Craig Wilen
WilenLab
Excited to share our new paper led by @chennifer_jen looking at the role of NSAIDs in #COVID19. NSAIDs dampen the cytokine and antibody response to SARS-CoV-2 infection @ASMicrobiology @JVirology @Yale_LabMed
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Dr. Ali Nouri
AliNouriPhD
1/The UK #SARSCoV2 variant reported to be 70% more transmissible harbors a set of mutations in the Spike protein––the part of the virus that touches the human ACE2 receptor and
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