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#Infectiousness
A Marm Kilpatrick
DiseaseEcology
Will vaccination reduce transmission or just disease?Do 3 vaccines w interim or final phase 3 results (Pfizer, Astrazeneca, Moderna) reduce asymptomatic infections & does reduced symptomatic infection imply reduced infections?Thread
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Rapid Tests
RapidTests
A new study shows rapid tests detect >85% of probable infectious cases (cases with high viral counts). The ability to detect these cases was just as good in symptomatic and
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A Marm Kilpatrick
DiseaseEcology
Viral loads (& age but not symptoms) influences transmission probability, incubation period & symptomatic/asymptomatic outcome.Fantastic new study @dr_michaelmarks. Tons to learn & haven't seen any detailed thread yet, so he
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Ryan McNamara 🧬
Ryan_Mac_Phd
Virus fragments can exert pathogenic effects inside a host, but that's distinct from being infectious.To be infectious, a virus particle must be intact. This includes the virus genome and the
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Allen Cheng
peripatetical
Why would we use a vaccine that mightn't prevent transmission? Should we use one particular vaccine, or roll out the vaccines we have as broadly and quickly as possible? I'd
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Phil Booth
EinsteinsAttic
Apropos of @thesundaytimes article, a few thoughts: firstly, as I tweeted 2 days ago & in stark contrast to the #transparency around other tech/data intitiatives - *cough* @NHSEngland #DataStore
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Dan Larremore
DanLarremore
Preprint: Viral surveillance testing is crucial, but not all surveillance strategies are equal. We modeled the impacts of test frequency, assay limit of detection, test turnaround time, measuring impact on
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Bill Hanage
BillHanage
Very interesting preprint on epidemiology of B.1.1.7 (or the 'Variant of concern' - VOC) in SE England. Have not fully digested but there are some important take homes 1/n https://cmmid.github.io/topics/covid19/reports/uk-novel-vari
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Rapid Tests
RapidTests
The FDA has a well-intentioned requirement for asymptomatic data.But that requirement greatly slows down progress on rapid tests, and new data suggests it isn't even necessary anymore! In light of
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David Dowdy
davidwdowdy
New piece on subclinical TB in @ATSBlueEditor by the thoughtful @emilyakendall and @soustha - ahead-of-print paywall (working on it), so here's a quick thread, using figures presented elsewhere.Many of these
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Marc Lipsitch
mlipsitch
From giving advice recently to a friend who was symptomatic, got tested and was told to expect a 3-5d delay, I've come to realize a gap in our prevention approach.
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Tom Dolphin
thomasdolphin
Hospital after hospital is activating surge plans and redeploying staff or declaring major incidents.We haven't even got to the part where Christmas gathering-related infections show up at the hospital yet.This
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Whitney R. Robinson
WhitneyEpi
1/ Maybe it’s my #epitwitter bias, but I get frustrated by the outsized attention these hospital-based viral load comparison studies (kids vs adults) get. And interpreted as children as a
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Michael Hobbes
RottenInDenmark
Weird how everyone with expertise in epidemiology, the CDC or the "damning" slide presentation in question doesn't agree with this account of events.https://twitter.com/Yascha_Mounk/status/1341866668528717824 This is the slide
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A Marm Kilpatrick
DiseaseEcology
ALOHA may be in troubleStart. Aug 1 you can go to Hawaii w/out 14d quarantineJust $150 to get #COVID19 test 72 hrs before flight & if negative & no fever
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Benjamin Mazer
BenMazer
I think it's become clear that rapid antigen testing for COVID19 proponents are simply unserious. They prop up a straw man: that lab medicine impractically worships the god of sensitivity.
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